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Fluorescein angiography (FA) is a classic diagnostic test that involves taking photographs of the blood vessels in the eye with the help of a contrast dye. Fluorescein is a yellow dye that glows in the retina’s blood vessels when exposed to a certain wavelength of visible light.
These images can help evaluate or detect serious eye conditions such as:
During these exams, the patient’s pupils are dilated with eye drops. The contrast dye is then injected, usually into a vein in the patient’s arm. The dye travels up to the eye within a few seconds and “lights up” the blood vessels for the camera to take multiple photographs.
Fluorescein dye angiography is considered safe for the vast majority of patients. Fluorescein dye does not contain iodine and can generally be used in patients who have reactions to other intravenous contrast dyes.
Fluorescein dye angiography is generally safe and well-tolerated, though mild reactions such as itching, nausea, or rash can occur. These symptoms can usually be managed with oral medication if severe.
Patients who receive fluorescein injections can expect their urine to appear bright orange for the first several hours after the test.
Fluorescein dye angiography can take around 10 to 30 minutes from start to finish. Most of that time includes pupil dilation, injection, and photo imaging. The duration may vary slightly depending on the patient’s condition and the rate at which the dye circulates through the eye.

Your doctor can evaluate the health of the retina using this imaging technology. FA allows your doctor to detect diseases of the retina at early stages and has made timely intervention possible in a number of retinal conditions. FA may be required intermittently to assess a patient’s response to treatment or need for further therapy.
Browse through the articles on this page to explore a wide range of topics related to retinal health. Visit other pages on our site, including our retinal disease page, for additional information as well.
Mid Atlantic Retina is made up of top Wills Eye Physicians, known for being the best retina doctors in the country. To seek further retina information and personalized care from a board-certified retinal specialist, make an appointment at one of our convenient locations in the Pennsylvania, Delaware, or New Jersey area. Our specialists offer the most advanced treatments for adult and pediatric retinal diseases, and we pride ourselves on providing all of our patients with the highest level of care. This includes efficient diagnostics and the latest in treatments and procedures, with state-of-the-art services tailored to your needs.
Contact us today to schedule your first appointment.