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Fundus autofluorescence is a non-invasive diagnostic test that involves taking digital photographs of the back of the eye without a contrast dye.  These images can help with the early detection of diseased retina in serious eye conditions such as macular degeneration, hereditary retinal degenerations, and retinal toxicity from the long-term use of medications such as hydroxychloroquine (plaquenil).

Geographic Atrophy due to Advanced Dry Macular Degeneration

Fluorophores are chemical structures that possess fluorescent properties when exposed to light of a particular wavelength.  Lipofuscin is a fluorophore that accumulates with age but can also occur from cell dysfunction.  When excited with short to medium wavelengths of visible light, lipofuscin  autofluoresces (glows).  Autofluorescence imaging uses this technology to record fluorescence that occurs naturally in the eye or accumulates as a result of disease.  Fundus autofluorescence uses light to produce images, rather than radiation, sound, or radiofrequency waves.  As a result, there is no risk to the patient or harmful side effects.

Your doctor can evaluate the health of the retina using this imaging technology.  This technology allows your doctor to detect diseases of the retina at early stages and has made timely intervention possible in a number of retinal conditions.  Fundus autofluorescence imaging may be performed multiple times to monitor the progression of retinal diseases, need for intervention and response to treatment.

Fundus autofluorescence is non-invasive, fast diagnostic test that usually takes only a few minutes to perform in your doctor’s office.


2022 ASRS Annual Meeting Wrap-Up

The American Society of Retina Specialists (ASRS) recently held its annual meeting in New York City where multiple...

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Carl Regillo, MD speaks with PBS on the treatment and upcoming research of Age-Related Macular Degeneration

    Age-Related Macular Degeneration, or AMD, is a leading cause of vision loss for people 50 years...

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Wills Eye Hospital Newsletter: Spring 2022

Wills Eye Hospital recently released the Spring issue of Eye Level, their digital newsletter. The newsletter features Mid Atlantic...

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Schedule an Appointment with a Mid Atlantic Retina Specialist

Browse through the articles on this page to explore a wide range of topics related to retinal health. Visit other pages on our site, including our retinal disease page, for additional information as well.

Mid Atlantic Retina is made up of top Wills Eye Physicians, known for being the best retina doctors in the country. To seek further retina information and personalized care from a board-certified retinal specialist, make an appointment at one of our convenient locations in the Pennsylvania, Delaware, or the New Jersey area. Our specialists offer the most advanced treatments for adult and pediatric retinal diseases, and we pride ourselves on providing all of our patients with the highest level of care. This includes efficient diagnostics and the latest in treatments and procedures, with state-of-the-art services tailored to your needs.

Contact us today to schedule your first appointment.